A Mab A Case Study In Bioprocess Development Access

Before a single cell is cultured, the process development team defines the Target Product Profile. For Mab-X, the goal is to treat moderate-to-severe rheumatoid arthritis. The TPP dictates:

For mAb-X, we utilized . This is the workhorse of mAb purification because Protein A binds specifically to the Fc region of antibodies, ignoring almost everything else (host cell proteins, DNA, viruses). A Mab A Case Study In Bioprocess Development